Region championships will be on the line in several games around the state in the final weekend of the regular season. Among those are Lowndes vs. Valdosta in 1-6A, Douglas County vs. Carrollton in 2-6A, Sandy Creek vs. Troup in 2-3A, Westside-Augusta vs. West Laurens in 4-3A, and Hebron Christian vs. Prince Avenue Christian in 8-2A.

Region titles will be on the line Friday night when Central (Carrollton) meets Griffin in 3-4A and Rome travels to New Manchester in 5-5A. But plenty more champions could be crowned this weekend, including Athens Academy (8-A Division I), Kell (6-4A), Thomas County Central (2-5A), North Gwinnett (7-6A), Peach County (1-3A) and Gainesville (7-5A).

Undefeated Powder Springs rivals McEachern and Hillgrove will go head-to-head for sole possession of first place in Region 3-6A in one of Week 10's best matchups. Undefeated top-10 teams Hughes and Northgate will battle to retain at least a share of first place in Region 3-5A game, and Troup and LaGrange resume their rivalry in Class 3A.

First place will be on the line in Week 9 when undefeated teams in region play match up in Friday night in eight regions across the state. Among those are four games featuring two top-10 teams - 1-2A (Carver-Columbus at Sumter County); 2-A Division II (Clinch County at Brooks County); 7-5A (Gainesville at Milton); and 6-3A (North Hall at Greater Atlanta Christian).

Although it's still relatively early in the region portion of the 2025 season, front-runner status will be at stake in several regions across the state in Week 8. Among those are 4-2A (Burke County at Thomson), 7-4A (Cartersville at Cass), 7-6A (North Gwinnett at Peachtree Ridge) and 1-A Division I (Thomasville at Worth County).

South Georgia matchups headline the schedule for Week 7 of the regular season. Four top-10 teams from Region 1-6A will go to head-to-head when Colquitt County travels to Lowndes and Valdosta visits Camden County. Lee County will face Thomas County Central in a matchup of top-10 teams in Region 2-5A, and Benedictine will visit Ware County for front-runner status in Region 1-4A.

The four remaining unbeaten teams in Region 4-3A play will go head-to-head for a share of first place Friday night when West Laurens travels to Harlem and Westside-Augusta visits Aquinas for Week 6 games. Front-runner status in other region also will be decided, including Calvary Day at Jenkins in 3-3A, Denmark at West Forsyth in 6-6A, Fitzgerald at Worth County in 1-A Division I, and North Cobb at North Paulding in 5-6A.

Sprayberry travels to Sequoyah on Friday for a matchup of top-10 teams in Class 5A that will establish the favorite to win the Region 6. Sprayberry won last year and took the region title, although both teams made it to the state quarterfinals. No. 2 Buford hosts No. 4 Douglas County in a high-profile Class 6A non-region game, and Calhoun goes to Jefferson for a game featuring two state finalists from 2024.

Region play heats up in Week 4 as Stockbridge and Eagle's Landing of 2-4A, Whitewater and Troup of 2-3A and Ringgold and Rockmart of 7-2A meet to determine the early pecking order in their playoff races. Elsewhere, south Georgia rivals Thomas County Central and Thomasville will face off for the 58th time.

Two of Georgia's defending state champions will be tested by top out-of-state competition Friday night when Thompson of Alabama visits Grayson and McCallie of Tennessee hosts Hebron Christian in top Week 3 action. Cherokee Bluff and North Hall will battle for supremacy in Hall County, and Colquitt County travels to North Gwinnett to renew a North-South rivalry.

Grayson and Rabun Gap, two of the top four Georgia teams in the High School Football America rankings, will headline the Week 2 schedule when they meet Friday night at Grayson. Elsewhere, North Cobb and McEachern will battle for Cobb County supremacy, and the private schools feature strong matchups that include Hebron Christian vs. Fellowship Christian, Holy Innocents’ vs. Blessed Trinity, and Westminster vs. Pace Academy.